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Related Experiment Video

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Quantification of noninvasive fat reduction: A systematic review.

Sogyong L Auh1, Sanjana Iyengar2, Alexandra Weil2

  • 1Section of Dermatology, University of Chicago Medicine, Chicago, Illinois.

Lasers in Surgery and Medicine
|December 7, 2017
PubMed
Summary

Quantifying noninvasive fat reduction is challenging due to limitations in current measurement methods. This review assesses various techniques for measuring subcutaneous fat changes, highlighting their respective drawbacks.

Keywords:
adipocytolysiscryolipolysisfatmeasurementnon-invasivequantificationradiofrequencyreductionsystematic reviewultrasound

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Area of Science:

  • Aesthetic Medicine
  • Medical Imaging
  • Body Composition Analysis

Background:

  • Noninvasive fat reduction methods are increasingly popular.
  • Accurate quantification of subcutaneous fat changes is crucial for assessing treatment efficacy.
  • Existing measurement techniques present various limitations.

Purpose of the Study:

  • To conduct a comparative review of utility measures for subcutaneous fat.
  • To assess the effectiveness of different methods in quantifying noninvasive fat reduction.

Main Methods:

  • Systematic literature search of multiple electronic databases (MEDLINE, EMBASE, CINAHL, Scopus).
  • Inclusion of randomized controlled trials and cohort studies with original data and at least 10 subjects.
  • Screening and manual review of 1,057 retrieved articles, with 36 meeting the criteria.

Main Results:

  • Thirty-six studies met the inclusion criteria, utilizing diverse measurement techniques.
  • Commonly reported methods included circumference measurements, caliper thickness, ultrasound, MRI, and 3D photography.
  • Subjective methods like photographic evaluation and patient satisfaction surveys were also employed.

Conclusions:

  • All current methods for quantifying noninvasive fat reduction have significant limitations.
  • Photographic comparisons are subjective, circumference/caliper measurements are confounded, ultrasound is operator-dependent, and MRI is costly.
  • Development of reliable, accurate, and practical subcutaneous fat measurement tools is needed as technology advances.