Related Experiment Video
Updated: Feb 17, 2026

A Model of Cardiac Remodeling Through Constriction of the Abdominal Aorta in Rats
Published on: December 2, 2016
Renal adaptation to the failing heart
Abstract:
Preview In patients with congestive heart failure, a diversity of neurohumoral and renal responses are involved in the maintenance of effective circuiting blood volume. The major clinical consequences of these responses are edema formation and, ultimately, decreased renal perfusion. In this article, the authors review the mechanisms that affect renal function in patients with systolic heart failure. A companion article on page 153 discusses use of therapeutic agents that modify these pathophysiologic sequelae.
Related Concept Videos
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Heart Failure II: Pathophysiology
Heart Failure Drugs: Diuretics
Heart Failure V: Medical Management
Pathophysiology of Heart Failure
Heart Failure VI: Adjunct Therapies

