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Published on: January 7, 2019
Cognitive, functional and behavioral assessment: Alzheimer's disease
Márcia L F Chaves1, Claudia C Godinho1, Claudia S Porto2
1Neurology Service of the Hospital de Clínicas of Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre RS, Brazil.
This review recommends validated cognitive and functional assessment tools for diagnosing Alzheimer's disease (AD) dementia in Brazil. It provides evidence-based guidance on selecting appropriate tests for various assessment needs.
Area of Science:
- Neurology
- Geriatrics
- Psychometrics
Background:
- Accurate diagnosis of Alzheimer's disease (AD) dementia relies on comprehensive cognitive, functional, and behavioral assessments.
- Standardized and validated tools are crucial for consistent diagnosis and severity assessment across different populations.
- Brazil requires specific recommendations for assessment tools adapted and validated for its population.
Purpose of the Study:
- To review and update recommendations for cognitive, functional, and behavioral assessment tools for diagnosing dementia due to AD in Brazil.
- To provide an evidence-based selection of validated tests and batteries for the Brazilian context.
- To guide clinicians in choosing appropriate assessment instruments based on cognitive domain and functional status.
Main Methods:
- A systematic literature review was conducted using MEDLINE, LILACS, and SCIELO databases.
- Expert panels analyzed studies on the validation and adaptation of tests for the Brazilian population.
- Studies were classified according to their level of evidence to support recommendations.
Main Results:
- Recommended scales for instrumental activities of daily living include IQCODE, DAFS-R, DAD, ADL-Q, and Bayer scale; Katz scale for basic activities of daily living.
- Neuropsychiatric Inventory (NPI), CAMDEX, and Cornell scale for depression in dementia are useful for evaluating neuropsychiatric symptoms.
- Mini-Mental State Examination is recommended for screening; multifunctional batteries (CAMCOG-R, ADAS-COG, CERAD, MDRS) for brief cognitive evaluations; CDR scale for clinical and severity assessment.
Conclusions:
- Evidence supports the use of specific, validated assessment tools for diagnosing dementia due to AD in Brazil.
- Recommendations cover a range of assessments, from basic and instrumental daily living activities to cognitive domains and neuropsychiatric symptoms.
- The review provides a practical guide for Brazilian clinicians to select appropriate diagnostic and severity assessment tools for Alzheimer's disease dementia.
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