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Published on: May 22, 2019
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Association among depression, cognitive impairment and executive dysfunction after stroke
Luisa Terroni1, Matildes F M Sobreiro1, Adriana B Conforto2
1Consultation-Liaison Psychiatry Group, Department and Institute of Psychiatry, Clinics Hospital, Medical School, University of São Paulo, São Paulo SP, Brazil.
Dementia & Neuropsychologia
|December 8, 2017
Summary
Post-stroke depression (PSD) is common and linked to worse cognitive impairment, especially in executive function. Early detection and treatment of PSD and cognitive issues in stroke survivors are crucial for better outcomes.
Area of Science:
- Neurology
- Psychiatry
- Rehabilitation Medicine
Background:
- Depression and cognitive impairment are frequent after stroke.
- The complex relationship between post-stroke depression (PSD) and cognitive impairment requires further elucidation.
Purpose of the Study:
- To review the relationship between post-stroke depression and cognitive impairment.
Main Methods:
- A systematic PubMed search was conducted for quantitative studies published in the last ten years.
- Studies focused on the relationship between PSD and cognitive impairment in stroke patients, using neuropsychological tests and depression assessments within three months post-stroke.
Main Results:
- Six studies met the criteria, showing PSD prevalence from 22% to 31%.
- PSD was associated with increased cognitive impairment (35.2%–87%), particularly affecting executive function, memory, language, and processing speed.
Conclusions:
- Executive dysfunction and depression are common in stroke survivors, often coexisting and linked to poorer prognosis.
- Early detection and treatment of PSD and executive dysfunction in stroke patients are essential for improved outcomes.

