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Association between common bile duct diameter and abdominal aorta calcium score
Yashar Moharamzad1, Sahar Abbasi1, Morteza Sanei Taheri2
1Department of Radiology, Shohada Hospital, Shahid Beheshti University of Medical Sciences, Tajrish Sq, Tehran, 1445613131, Iran.
Insights
Atherosclerosis, a condition linked to aging, is associated with a larger common bile duct (CBD) diameter. This study found a moderate correlation between abdominal aorta atherosclerosis and increased CBD diameter in asymptomatic patients.
Area of Science:
- Vascular Medicine
- Gastroenterology
- Radiology
Background:
- Aging is linked to an increased normal upper limit of the common bile duct (CBD) diameter.
- Atherosclerosis, a common aging-related condition, may influence CBD diameter by affecting smooth muscle contractility and blood flow.
Purpose of the Study:
- To investigate the association between CBD diameter and abdominal aorta (AA) atherosclerosis.
Main Methods:
- 99 asymptomatic patients without a history of cholecystectomy underwent contrast-enhanced CT scans.
- CBD diameter was measured, and AA atherosclerosis was quantified using the Agatston score.
Main Results:
- Patients with AA atherosclerosis (Agatston score > 0) had a significantly larger mean CBD diameter (7.39 ± 2.07 mm) compared to those without calcification (5.29 ± 1.32 mm).
- A moderate positive correlation was observed between CBD diameter and the Agatston score (ρ = 0.43, P = 0.005).
Conclusions:
- Atherosclerosis may contribute to an increased CBD diameter, potentially due to effects on smooth muscle.
- Further research is needed to determine if upper limits for normal CBD diameter should be adjusted for patients with subclinical or clinical atherosclerosis.
Background And Objective:
There is evidence of association between aging and increase in the normal upper limit of the common bile duct (CBD) diameter. As aging is a documented risk factor for atherosclerosis, and the possible effect that atherosclerosis can have on the CBD diameter via affecting its smooth muscle contractility and blood flow, we decided to determine the association between CBD diameter and atherosclerosis in the abdominal aorta (AA).
Methods:
A total of 99 asymptomatic patients (53 males and 46 females; age range of 18-88 years) without history of cholecystectomy who underwent abdominal contrast-enhanced CT scan were included. The CBD diameter was measured. The atherosclerosis of AA was quantified by Agatston score.
Results:
Mean (± SD) CBD diameter was 6.14 (± 1.95) mm; range = 2.4-12.7 mm. Agatston score was 0 in 59 patients. In the remaining 40 patients, median (interquartile range, IQR) Agatston score was 497.5 (2026.3). Mean (± SD) CBD diameter in patients with Agatston score > 0 was 7.39 (± 2.07) mm compared to 5.29 (± 1.32) mm in patients without calcification plaque (P < 0.001). A moderate correlation was seen between CBD diameter and Agatston score (ρ = 0.43; P = 0.005).
Conclusion:
Although the exact cause of increased CBD diameter with advancing age is not understood, a general atherosclerotic process which occurs with aging may affect smooth muscle of the CBD. Whether an upper limit for normal CBD should be defined or not when evaluating dilated CBD for patients with subclinical or clinical atherosclerosis needs further studies.
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