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Cutting Edge Methods for Non-Invasive Disease Diagnosis Using E-Tongue and E-Nose Devices
Jessica Fitzgerald1, Hicham Fenniri2
1Department of Chemical Engineering, Northeastern University, 313 Snell Engineering Center, 360 Huntington Avenue, Boston, MA 02115, USA. fitzgerald.je@husky.neu.edu.
Biosensors
|December 8, 2017
Summary
Biomimetic cross-reactive sensor arrays (B-CRSAs) offer a non-invasive method for disease diagnosis. Recent advancements have made these "electronic noses and tongues" selective, sensitive, and affordable alternatives for medical diagnostics.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
- Medical Diagnostics
Background:
- Biomimetic cross-reactive sensor arrays (B-CRSAs) analyze patient samples for disease detection.
- Technological progress has enhanced B-CRSAs' selectivity, sensitivity, and affordability.
- B-CRSAs show promise as non-invasive alternatives to current diagnostic standards.
Purpose of the Study:
- To review recent advancements in B-CRSAs for disease diagnostics.
- To provide an outlook on future technological developments in B-CRSAs.
- To highlight the application of B-CRSAs in detecting metabolic disorders, mental health diseases, and cancer.
Main Methods:
- Review of recent literature on Biomimetic cross-reactive sensor arrays (B-CRSAs).
- Analysis of technological improvements in sensor selectivity and sensitivity.
- Assessment of cost-effectiveness and non-invasive diagnostic capabilities.
Main Results:
- B-CRSAs have demonstrated success in diagnosing diverse diseases from vapor and liquid samples.
- Significant improvements in sensor technology have been observed over the past decade.
- The development of accurate and non-invasive diagnostic devices is rapidly progressing.
Conclusions:
- B-CRSAs represent a feasible and improving alternative to traditional medical diagnostics.
- Future developments are expected to further enhance the capabilities and applications of B-CRSAs.
- The review highlights the growing importance of B-CRSAs in personalized medicine and early disease detection.

