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Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
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Lung transplantation in elderly patients.
Andrew Courtwright1, Edward Cantu2
1Division of Pulmonary and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
Journal of Thoracic Disease
|December 10, 2017
Summary
Lung transplantation is increasingly performed in older adults, challenging previous age restrictions. This review examines outcomes and selection factors for elderly lung transplant recipients.
Area of Science:
- Medicine
- Pulmonology
- Transplantation
Background:
- Older age was traditionally a contraindication for lung transplantation.
- Demographic shifts and evolving allocation scores have changed this practice.
Purpose of the Study:
- To review current lung transplantation practices in elderly patients.
- To discuss factors influencing increased transplantation in older adults.
- To analyze outcomes, including survival and quality of life, and selection criteria.
Main Methods:
- Literature review on lung transplantation in elderly populations.
- Analysis of factors influencing candidate and procedure selection.
- Evaluation of outcomes data for older transplant recipients.
Main Results:
- Lung transplantation in older adults is increasing.
- Outcomes in elderly recipients are becoming better understood.
- Careful selection is crucial for successful outcomes.
Conclusions:
- Age is a less significant barrier to lung transplantation than previously thought.
- Careful patient and procedure selection optimizes outcomes for elderly recipients.
- Further research can refine selection criteria and improve results.
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