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Published on: August 30, 2018
Healthcare-acquired infections: prevention strategies
Shelanah A Fernando1, Timothy J Gray1, Thomas Gottlieb1
1Department of Microbiology & Infectious Diseases, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Abstract:
Healthcare-acquired infections (HAI) impact on patient care and have cost implications for the Australian healthcare system. The management of HAI is exacerbated by rising rates of antimicrobial resistance (AMR). Health-care workers and a contaminated hospital environment are increasingly implicated in the transmission and persistence of multi-resistant organisms (MRO), as well as other pathogens, such as Clostridium difficile. This has resulted in a timely focus on a range of HAI prevention actions. Core components include antimicrobial stewardship, to reduce overuse and ensure evidence-based antimicrobial use; infection prevention strategies, to control MRO - particularly methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus spp. (VRE) and, more recently, multi-resistant Gram-negative bacteria; enhanced institutional investment in hand hygiene; hospital cleaning and disinfection; and the development of prescribing guidelines and standards of care. AMR surveillance and comparisons of prescribing are useful feedback activities once effectively communicated to end users. Successful implementation of these strategies requires cultural shifts at local hospital level and, to tackle the serious threat posed by AMR, greater co-ordination at a national level. HAI prevention needs to be multi-modal, requires broad healthcare collaboration, and the strong support and accountability of all medical staff.
Insights
Healthcare-acquired infections (HAI) are a significant concern, worsened by antimicrobial resistance (AMR). Effective prevention requires coordinated national strategies, improved hygiene, and antimicrobial stewardship to protect patients and the healthcare system.
Area of Science:
- Infectious Diseases
- Public Health
- Healthcare Management
Background:
- Healthcare-acquired infections (HAI) pose a significant burden on patient care and Australian healthcare costs.
- Rising antimicrobial resistance (AMR) complicates HAI management, with healthcare workers and environments implicated in pathogen transmission.
- Multi-resistant organisms (MRO), including MRSA, VRE, and Gram-negative bacteria, are a growing concern.
Purpose of the Study:
- To outline essential strategies for preventing healthcare-acquired infections (HAI) in the context of rising antimicrobial resistance (AMR).
- To emphasize the need for a multi-modal approach involving antimicrobial stewardship, infection prevention, and enhanced hygiene practices.
- To highlight the importance of national coordination and cultural shifts for successful HAI prevention.
Main Methods:
- Review of current HAI prevention strategies, including antimicrobial stewardship and infection control measures.
- Focus on controlling multi-resistant organisms (MRO) through enhanced hygiene, cleaning, and disinfection.
- Analysis of the role of prescribing guidelines, AMR surveillance, and feedback mechanisms.
Main Results:
- Core prevention actions include antimicrobial stewardship, infection prevention for MRO, enhanced hand hygiene, and hospital disinfection.
- AMR surveillance and prescribing comparisons are valuable when communicated effectively to end-users.
- Successful implementation necessitates cultural changes at the hospital level and national coordination.
Conclusions:
- Effective HAI prevention requires a multi-modal strategy involving broad healthcare collaboration.
- Strong support and accountability from all medical staff are crucial for success.
- Addressing the threat of AMR demands greater national-level coordination of HAI prevention efforts.
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