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Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
Published on: October 3, 2018
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Severe pyoderma gangrenosum caused by myelodysplastic syndrome successfully treated with decitabine administered by a
Mostafa F M Saleh1,2, Yogen Saunthararajah1
1Department of Hematology and Oncology Taussig Cancer Institute Cleveland Clinic Cleveland Ohio.
Clinical Case Reports
|December 12, 2017
Abstract:
Pyoderma gangrenosum (PG) is a morbid necrotizing neutrophilic dermatoses for which current treatments are inadequate. Here, we describe the use of a novel noncytotoxic regimen of the deoxycytidine analog decitabine to treat underlying myeloid malignancy causing PG, to thereby produce safe and effective resolution of extensive PG.