Spectral-Domain Optical Coherence Tomography Angiography for the Diagnosis and Evaluation of Polypoidal Choroidal
Talisa E de Carlo1,2,3,4,5, Gregg T Kokame3,4,5,6, Jessica G Shantha3,4,5
1University of Hawaii Transitional Residency Program, Department of Medicine, University of Hawaii School of Medicine, Honolulu, Hawaii, USA.
Purpose:
To compare the diagnostic ability of optical coherence tomography angiography (OCTA) with indocyanine green angiography (ICGA) in polypoidal choroidal vasculopathy (PCV).
Methods:
Retrospective review of 47 eyes with PCV imaged with ICGA and OCTA. For each eye, it was determined which imaging modality better delineated the PCV complex. The presence of a branching vascular network (BVN) and polyp(s) were noted.
Results:
PCV was better visualized with ICGA in 21 eyes (44.7%) and with OCTA in 9 eyes (19.2%). The results were comparable in 17 eyes (36.2%). Of the 44 eyes with BVN on ICGA, 41 eyes (93.2%) also showed BVN on OCTA. Of the 28 eyes with polyp(s) on ICGA, 22 eyes (78.6%) also showed polyp(s) on OCTA. Polyps were high-flow lesions or faint low-flow dilations on OCTA.
Conclusion:
OCTA readily detects BVNs and can detect most polyps, but in many cases ICGA is better able to detect the PCV complex.
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