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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
Liver-directed therapy for hepatocellular carcinoma
Kazim H Narsinh1,2, David P Duncan3, Isabel G Newton3
1Division of Interventional Radiology, Department of Radiology, University of California San Diego Medical Center, 200 W. Arbor Drive #8756, San Diego, CA, 92103, USA. knarsinh@ucsd.edu.
Abstract:
Liver-directed therapy is a critical component of treatment strategies for hepatocellular carcinoma. These therapies included percutaneous image-guided ablation, transarterial chemoembolization, and transarterial radioembolization, and are administered by interventional radiologists. Depending on the stage of disease, a particular treatment modality, or a combination thereof, is expected to be most efficacious in achieving the goals of treatment for a particular patient. This article seeks to review the various liver-directed treatment modalities for treatment of hepatocellular carcinoma, with attention to their efficacy and patient selection criteria.

