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Published on: February 9, 2022
[Characteristics of tidal breathing pulmonary function in children with tracheobronchomalacia]
Lan Li1, Qaing Chen, Fan Zhang
1Department of Respiration, Jiangxi Children's Hospital, Nanchang 330000, China. nclilan@163.com.
Insights
Children with tracheobronchomalacia (TBM) show distinct tidal breathing patterns, including faster breathing and altered expiratory flow timing. These pulmonary function changes tend to improve with age.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
Background:
- Tracheobronchomalacia (TBM) is a condition affecting the airways.
- Understanding its impact on breathing is crucial for diagnosis and management.
Purpose of the Study:
- To characterize tidal breathing pulmonary function in children diagnosed with TBM.
- To observe changes in pulmonary function over time post-diagnosis.
Main Methods:
- Compared 30 children with TBM to 30 healthy controls.
- Assessed tidal breathing pulmonary function at diagnosis and at 3, 6, 9, and 12 months.
Main Results:
- TBM group had higher respiratory rate and lower TPTEF/TE and VPTEF/VE ratios compared to controls.
- No significant differences in tidal volume or timing ratios were observed.
- TPTEF/TE and VPTEF/VE showed time-dependent improvement in TBM children.
Conclusions:
- Tidal breathing reveals characteristic alterations in children with TBM.
- Pulmonary function in TBM patients shows a tendency towards recovery with age.
Objective:
To investigate the characteristics of tidal breathing pulmonary function in children with tracheobronchomalacia (TBM).
Methods:
In this study, 30 children who were diagnosed with TBM using electronic bronchoscopy were enrolled in the observation group; 30 healthy children were recruited in the normal control group. For individuals in each group, the assessment of tidal breath pulmonary function was performed at diagnosis and 3, 6, 9, and 12 months after diagnosis.
Results:
There were no significant differences in tidal volume, inspiratory time, expiratory time, and inspiratory to expiratory ratio between the two groups (P>0.05). Compared with the control group, the observation group had a significantly higher respiratory rate and significantly lower ratio of time to peak tidal expiratory flow to total expiratory time (TPTEF/TE) and ratio of volume to peak tidal expiratory flow to total expiratory volume (VPTEF/VE). There was a time-dependent increase in TPTEF/TE and VPTEF/VE for TBM children from the time of initial diagnosis to 12 months after diagnosis.
Conclusions:
Tidal breathing pulmonary function has characteristic changes in children with TBM. Tidal breathing pulmonary function tends to be recovered with increased age in children with TBM.
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