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Current Progress and Controversies in Prostate Cancer Management.

De-Xin Dong1, Zhi-Gang Ji1

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This summary is machine-generated.

Optimal management for prostate cancer (PCa) is debated. This review covers current progress and controversies in PCa diagnosis, treatment, and prevention, highlighting the need for further research.

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Area of Science:

  • Oncology
  • Urology

Background:

  • Prostate cancer (PCa) management strategies are continuously evolving.
  • Optimal diagnostic and therapeutic approaches remain subjects of ongoing debate and research.

Purpose of the Study:

  • To systematically review current progress and controversies in prostate cancer (PCa) diagnosis, treatment, and prevention.
  • To identify areas requiring further investigation for improved PCa management.

Main Methods:

  • Systematic review of recently published articles up to July 2017.
  • Literature search using keywords: "prostate cancer," "progress," "controversy," "immunotherapy," and "prevention."

Main Results:

  • Serum prostate-specific antigen (PSA) screening is recommended for early PCa diagnosis in high-risk groups, though its value remains controversial.
  • Active surveillance is proposed for low-risk PCa, requiring further clinical validation.
  • Minimally invasive surgical techniques and radiotherapy are established treatments, while immunotherapy shows potential for altering the tumor microenvironment. Prevention strategies are crucial.

Conclusions:

  • Prostate cancer (PCa) diagnosis, treatment, and prevention are multifaceted challenges.
  • Further research is essential to refine management strategies and improve patient outcomes.