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Maternal recto vaginal colonization in term and preterm deliveries
Mostafa Javanian1, Zahra Akbarian Rad2, Mohsen Haghshenas Mojaveri2
1MD., Infectious Diseases and Tropical Medicine, Faculty Member, Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Electronic Physician
|December 15, 2017
Summary
Escherichia coli (E. coli) and gram-negative bacteria are more prevalent in preterm deliveries, highlighting the need for improved chemoprophylaxis strategies in pregnant women. This study compared maternal recto-vaginal colonization in term and preterm births.
Area of Science:
- Microbiology
- Obstetrics
- Neonatal Health
Background:
- Maternal recto-vaginal microorganisms are a primary cause of early-onset neonatal sepsis.
- Understanding colonization patterns is crucial for preventing infant infections.
Purpose of the Study:
- To identify common maternal recto-vaginal organisms.
- To compare colonization in term versus preterm deliveries.
Main Methods:
- Cross-sectional study of 511 pregnant women (≥26 weeks gestation) in Northern Iran.
- Recto-vaginal cultures collected and processed within 24 hours.
- Statistical comparison of microbial frequencies between term and preterm delivery groups.
Main Results:
- Escherichia coli (E. coli) was more frequent in preterm deliveries (68.1%) than term deliveries (52.5%).
- Group B Streptococcus was more common in term deliveries (13.7%) vs. preterm (3.2%).
- Staphylococcus epidermidis and E. coli were the most abundant organisms overall.
Conclusions:
- Higher E. coli and gram-negative bacteria prevalence in preterm deliveries warrants further investigation.
- The findings suggest a need to reassess chemoprophylaxis efficacy for preterm labor and prolonged membrane rupture.
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