Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

763
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
763
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

9.9K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
9.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gaining Insight Into the Nonfocality of Beta Oscillation Suppression Along the Sensorimotor Cortex Using Corticomuscular Coherence.

The European journal of neuroscience·2026
Same author

Anodal cerebellar tDCS does not alter beta oscillations or corticokinematic coherence in Friedreich's ataxia and healthy participants.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Aging increases the cortical resources allocated to static balance maintenance.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

The experience of cognitive conflict is intrinsically rewarding.

Communications psychology·2026
Same author

Untangling brain and behavioural measures of visual statistical learning: A longitudinal study in infancy.

Developmental cognitive neuroscience·2026
Same author

The infant brain rapidly entrains to visual statistical regularities during stimulus exposure.

Imaging neuroscience (Cambridge, Mass.)·2026
Same journal

Segmentation of the parasagittal dura mater on multi-center 3D-FLAIR MRI.

NeuroImage·2026
Same journal

Spatial frequency channels implement a mental ruler in spatial vision.

NeuroImage·2026
Same journal

Exploring the Link Between Intravoxel Incoherent Motion Measured Brain Diffusivity During Wakefulness and Sleep Macrostructure in the Elderly.

NeuroImage·2026
Same journal

Closed-loop adaptation of transcranial magnetic stimulation intensity with electroencephalography feedback.

NeuroImage·2026
Same journal

Volumetric postmortem MRI of the medial temporal lobe in Alzheimer's disease and related disorders: methodological advances and implications for in vivo biomarker development.

NeuroImage·2026
Same journal

Neural responses to equity and inequity when receiving vicarious rewards for self and charity during adolescence.

NeuroImage·2026
See all related articles

Related Experiment Video

Updated: Feb 16, 2026

Functional Mapping with Simultaneous MEG and EEG
06:04

Functional Mapping with Simultaneous MEG and EEG

Published on: June 14, 2010

18.5K

Contrasting functional imaging parametric maps: The mislocation problem and alternative solutions.

Mathieu Bourguignon1, Nicola Molinaro2, Vincent Wens3

  • 1Basque Center on Cognition, Brain and Language (BCBL), Donostia/San Sebastian, Spain; Laboratoire de Cartographie fonctionnelle du Cerveau, UNI - ULB Neuroscience Institute, Université libre de Bruxelles (ULB), Brussels, Belgium.

Neuroimage
|December 17, 2017
PubMed
Summary
This summary is machine-generated.

Neuroimaging contrasts mislocate brain activity sources. A new method accurately compares source locations, improving analysis of brain activity differences in magnetoencephalography (MEG) studies.

Keywords:
ContrastFunctional imagingLocation comparisonMagnetoencephalographyMislocation problemParametric maps

More Related Videos

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET
09:03

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET

Published on: October 22, 2019

11.0K
Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
07:13

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

1.7K

Related Experiment Videos

Last Updated: Feb 16, 2026

Functional Mapping with Simultaneous MEG and EEG
06:04

Functional Mapping with Simultaneous MEG and EEG

Published on: June 14, 2010

18.5K
Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET
09:03

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET

Published on: October 22, 2019

11.0K
Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
07:13

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

1.7K

Area of Science:

  • Neuroimaging
  • Computational Neuroscience
  • Brain Activity Analysis

Background:

  • Parametric map contrasts are common in neuroimaging for comparing conditions or populations.
  • These contrasts conflate amplitude and location differences, leading to inaccurate source localization.
  • Existing methods can misplace activity peaks, especially with smoother maps.

Purpose of the Study:

  • To highlight the mislocation problem in neuroimaging contrasts using magnetoencephalography (MEG) data.
  • To introduce a novel, dedicated method for comparing the locations of brain activity sources.
  • To evaluate the performance of the proposed location-comparison method.

Main Methods:

  • Simulations using reconstructed source maps from MEG recordings.
  • Quantitative assessment of contrast mislocation error under varying source distances.
  • Development and testing of a dedicated location-comparison algorithm.
  • Validation on real brain-speech entrainment data.

Main Results:

  • Contrast mislocation averaged ~10 mm when sources were at the same location.
  • Mislocation remained significant (>5 mm) even with sources 20 mm apart.
  • The proposed location-comparison method achieved ~90% sensitivity for 12 mm source separation.
  • Demonstrated utility on real-world brain-speech entrainment data.

Conclusions:

  • Contrasts of parametric maps offer unreliable information for precise source localization.
  • Dedicated methods are essential for accurately assessing location differences in brain activity.
  • The proposed location-comparison method provides a more precise alternative for neuroimaging analysis.