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Related Concept Videos

Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

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Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
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Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
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Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

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Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
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Kidney Transplant II: Surgical Procedure01:26

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Kidney Transplant III: Nursing Management01:16

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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

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Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
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A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
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Renal recovery.

Ivan Göcze1, Christina Wiesner1, Hans J Schlitt1

  • 1Department of Surgery and Operative Intensive Care, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.

Best Practice & Research. Clinical Anaesthesiology
|December 18, 2017
PubMed
Summary

Understanding acute kidney injury (AKI) recovery is crucial due to limited treatments. Renal functional reserve changes indicate kidney susceptibility, guiding strategies for faster recovery and preventing chronic kidney disease progression.

Keywords:
acute kidney diseaseacute kidney injurynephrology follow-uprecoveryrenal functional reserve

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Area of Science:

  • Nephrology
  • Renal Medicine
  • Critical Care

Background:

  • Limited preventive measures and specific therapies exist for acute kidney injury (AKI).
  • Renal functional reserve changes are a "hidden" indicator of kidney susceptibility to AKI and chronic kidney disease (CKD).
  • Understanding AKI recovery patterns is vital for managing kidney health.

Purpose of the Study:

  • To explore recovery patterns after acute kidney injury.
  • To understand the association between renal functional reserve and patient outcomes.
  • To identify strategies for facilitating recovery and preventing progression to CKD.

Main Methods:

  • This study focuses on analyzing recovery patterns and the role of renal functional reserve.
  • The research examines the association between these phenomena and patient outcomes.
  • Interventions are considered across different phases of the AKI continuum.

Main Results:

  • AKI recovery patterns are a key research focus due to limited interventions.
  • Renal functional reserve changes predict susceptibility to AKI and CKD.
  • Tailored interventions are needed for different AKI phases to optimize outcomes.

Conclusions:

  • Effective AKI management requires early recognition, prevention of secondary insults, and treatment to facilitate recovery.
  • Strategies should address distinct phases: prevention, early AKI management, and promoting recovery.
  • Understanding renal functional reserve is key to preventing AKI progression to CKD.