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Updated: Feb 16, 2026

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
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Characteristics and application of S1-P1 nucleases in biotechnology and medicine

Tomáš Koval1, Jan Dohnálek1

  • 1Institute of Biotechnology of the Czech Academy of Sciences, v. v. i., Biocev, Průmyslová 595, 252 50 Vestec, Czech Republic.

Biotechnology Advances
|December 18, 2017
PubMed

Keywords:
Cancer treatmentHeteroduplex cleavageHost-pathogen interactionLeishmaniasisNuclease protection assayProtozoan parasitesS1–P1 nucleaseSingle-nucleotide mismatchStructure-function relationshipTILLING

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