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Related Concept Videos

Reticular Dermis01:15

Reticular Dermis

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Changes in Skin Color: Clinical Perspectives01:14

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
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Renewal of Skin Epidermal Stem Cells01:12

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The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
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Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Related Experiment Video

Updated: Feb 16, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

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[What's new in dermatological research?]

P-E Stoebner1

  • 1Institut des biomolécules Max-Mousseron, CNRS UMR5247, université Montpellier, 30029 Nîmes, Cedex 9, France; service de dermatologie, CHU Carémeau, place du Professeur-Robert-Debré, 30029 Nîmes, Cedex 9, France.

Annales De Dermatologie Et De Venereologie
|December 19, 2017
PubMed
Summary

This review highlights key 2016-2017 dermatological research, focusing on artificial intelligence in image recognition, atopic dermatitis, wound repair, and hair growth. It covers new insights into melanomagenesis, epidermolysis bullosa simplex, and drug eruptions.

Keywords:
CicatrisationDermatologieDermatologyMelanomagenesisMélanomagenèsePathophysiologyPhysiopathologieRecherche translationnelleTranslational researchWound repair

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Area of Science:

  • Dermatology
  • Medical Research

Background:

  • A review of significant dermatological research published between September 2016 and August 2017.
  • Focuses on studies with the potential to alter clinical practice or advance understanding of disease mechanisms and treatments.

Purpose of the Study:

  • To present a curated selection of impactful dermatological research.
  • To highlight advancements in understanding and treating various skin conditions.

Main Methods:

  • Selection of relevant manuscripts from a specific one-year period.
  • Thematic organization of research findings into key areas of dermatology.

Main Results:

  • Advances in artificial intelligence for dermatological image recognition.
  • New insights into the pathophysiology and management of atopic dermatitis.
  • Progress in understanding wound repair and the hair growth cycle.
  • Updated data on melanomagenesis, epidermolysis bullosa simplex, and drug eruptions.

Conclusions:

  • The selected research offers novel pathophysiologic mechanisms and therapeutic approaches.
  • These findings have the potential to significantly impact dermatological practice.