Related Experiment Video
Updated: Feb 16, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
Published on: June 7, 2015
An automated dose tracking system for adaptive radiation therapy
Chang Liu1, Jinkoo Kim2, Akila Kumarasiri1
1Department of Radiation Oncology, Josephine Ford Cancer Institute, Henry Ford Health System, Detroit, MI, USA.
An automated dose tracking system streamlines adaptive radiation therapy (ART) by significantly reducing manual effort and computation time. This innovation facilitates the routine clinical application of ART for enhanced radiation therapy effectiveness.
Area of Science:
- Medical Physics
- Radiation Oncology
- Clinical Engineering
Background:
- Implementing adaptive radiation therapy (ART) in clinical practice presents significant technical and resource challenges.
- Validating each step of the ART process is crucial for its successful integration.
Purpose of the Study:
- To identify key components of adaptive radiation therapy (ART).
- To demonstrate how an automated procedure enhances ART efficiency.
- To promote the routine clinical use of ART.
Main Methods:
- Developed in-house software with modular components (ART engine, user tools, integration tools) for automated dose tracking.
- Utilized C++ and C# for independent program modules within a distributed Windows environment.
- Integrated custom GUIs for user interaction, including deformable image registration (DIR), and a scripting API for automated dose calculation.
Main Results:
- Retrospectively evaluated on 20 prostate and 96 head and neck cancer patients; prospectively on 4 head and neck cancer patients.
- Processed 780 prostate and 2586 head and neck cancer dose fractions, including DIR and dose mapping.
- Achieved average daily cumulative dose computation in 3 hours with only 13 minutes of manual work per case.
Conclusions:
- Presented an efficient and user-friendly dose tracking system for clinical adaptive radiation therapy (ART).
- The automated software and processes were rigorously validated using patient data.
- Automation significantly improved efficiency, enabling routine clinical application of ART to enhance treatment outcomes.
Related Concept Videos
Therapeutic Drug Monitoring: Drug Analysis Methods
Therapeutic Drug Monitoring: Overview and Classification
Dosage Regimen: Fixed Dose
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Therapeutic Drug Monitoring: Affecting Factors

