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Chronic Pharyngitis

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Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Inflammation

Chronic Obstructive Pulmonary Disease-I: Introduction

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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

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Chronic nasal dysfunction.

R Jankowski¹, D T Nguyen¹, A Russel¹

¹Service ORL et chirurgie cervicofaciale, hôpital de Brabois, centre hospitalier régional universitaire de Nancy, université de Lorraine, bâtiment Louis-Mathieu, 54500 Vandoeuvre-les-Nancy, France.

European Annals of Otorhinolaryngology, Head and Neck Diseases

|December 19, 2017

Summary

This summary is machine-generated.

Chronic nasal dysfunction, based on evo-devo theory, redefines sinonasal disease management by treating the nose as three distinct organs. This approach offers personalized treatments for conditions like chronic rhinosinusitis.

Keywords:

Chronic rhinosinusitis Endoscopic sinus surgery Ethmoid Nasal obstruction Nasal polyps Olfaction

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Area of Science:

Otorhinolaryngology
Developmental Biology
Medical Theory

Background:

Current sinonasal disease management often uses a unified approach.
The evo-devo theory posits the nose comprises three distinct organs: olfactory, respiratory, and paranasal sinuses.
Existing diagnostic and therapeutic strategies may not fully address the distinct physiologies of these nasal components.

Purpose of the Study:

To introduce and elaborate on the clinical concept of chronic nasal dysfunction.
To propose an alternative diagnostic and therapeutic framework for sinonasal diseases.
To challenge the conventional understanding of the ethmoid's classification and its implications for surgical interventions.

Main Methods:

Application of the evo-devo (evolutionary developmental biology) theory to sinonasal anatomy and physiology.
Development of the chronic nasal dysfunction concept for etiological diagnosis.
Analysis of symptom independence based on the distinct origins and functions of the olfactory nose, respiratory nose, and paranasal sinuses.
Re-evaluation of surgical approaches like functional endoscopic endonasal surgery (FEES) in light of the evo-devo framework.

Main Results:

Chronic nasal dysfunction theory enables etiological diagnosis by considering the pathophysiological independence of nasal symptoms.
This concept facilitates tailored treatments addressing specific diseased nasal organs.
The evo-devo perspective clarifies that the ethmoid is not a sinus, impacting the scope of functional endoscopic sinus surgery (FESS).

Conclusions:

The chronic nasal dysfunction concept provides a novel framework for managing sinonasal diseases.
It offers an alternative to the chronic rhinosinusitis paradigm, emphasizing organ-specific diagnosis and treatment.
This approach refines understanding of nasal anatomy and surgical indications, particularly regarding the ethmoid structure.