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Updated: Feb 16, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Extramammary Paget's disease in an HIV-positive patient
Constantin Căruntu1, Sabina Andrada Zurac, GheorghiŢă Jugulete
1Department of Pathology, "Colentina" Clinical Hospital, Bucharest, Romania; sabina_zurac@yahoo.com.
Abstract:
Extramammary Paget's disease (EMPD) is an uncommon intraepithelial carcinoma usually found as an irregular, pruritic plaque on the apocrine-rich anogenital skin. Diagnosis of EMPD is challenging due to the rarity of the disease and the uncharacteristic clinical aspect and requires histopathological confirmation. We report the case of a 62-year-old human immunodeficiency virus (HIV)-positive male, which presents with a lesion of the left part of pubic area with clinical and dermatoscopic appearance suggestive for Bowen's disease but with histopathological diagnosis of EMPD. We present pathological and immunohistochemical data to confirm the diagnosis.
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