Related Experiment Video
Updated: Feb 16, 2026
14:24
Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
Published on: January 21, 2018
12.2K
Heart failure following oncological treatment
James Marangou1, Andrew Redfern2, Tony Haddad3
1Department of Cardiology, Fiona Stanley Hospital, Murdoch, Western Australia.
Current Opinion in Cardiology
|December 19, 2017
Summary
Cardio-oncology advances offer new ways to manage cancer treatments that can harm the heart. This review covers risk prediction, monitoring, and prevention strategies for heart failure in cancer patients.
Area of Science:
- Cardiology
- Oncology
- Cardio-oncology
Background:
- Cancer therapies, especially targeted and immunotherapies, improve outcomes but increase cardiac toxicity risk.
- Cardiac toxicity can lead to heart failure, a significant concern in cancer survivorship.
- Recent progress has been made in managing and preventing treatment-related cardiac issues.
Purpose of the Study:
- To provide an updated overview of cardio-oncology.
- To discuss oncological treatments with cardiac risk.
- To focus on heart failure prevention and management in cancer patients.
Main Methods:
- Review of recent advancements in cardio-oncology.
- Analysis of risk prediction strategies.
- Evaluation of imaging and biomarker monitoring techniques.
Main Results:
- Newer cancer treatments pose risks for cardiac toxicity and heart failure.
- Imaging and biomarkers aid in early detection of subclinical cardiac issues.
- Prevention and treatment strategies are evolving for at-risk patients.
Conclusions:
- Clinicians need guidance for monitoring and therapy selection in cancer patients.
- Management should consider pre-existing cardiac conditions and predicted toxicity risk.
- Cardio-oncology aims to balance cancer treatment efficacy with cardiac safety.
Related Concept Videos
01:30Heart Failure VII: Nursing Interventions
549
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
549
01:27Heart Failure I: Introduction
969
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
969
01:17Pathophysiology of Heart Failure
4.0K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
4.0K
01:30Heart Failure V: Medical Management
369
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
369
01:29Heart Failure II: Pathophysiology
1.0K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.0K
01:26Heart Failure III: Clinical Manifestations
648
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
648