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Updated: Feb 16, 2026

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
TRAFFIC ACCIDENT-RELATED OPEN GLOBE INJURIES
Yoshifumi Okamoto1,2, Shohei Morikawa1,2, Fumiki Okamoto1,2
1Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Ibaraki.
Open globe injuries from traffic accidents show better visual outcomes than typical cases. Initial visual acuity is a key predictor of final results, with no endophthalmitis observed in these patients.
Area of Science:
- Ophthalmology
- Trauma Surgery
- Public Health
Background:
- Open globe injuries are severe ocular emergencies.
- Traffic accidents represent a significant cause of traumatic eye injuries.
- Understanding injury mechanisms and outcomes is crucial for prevention and treatment.
Purpose of the Study:
- To analyze clinical features and visual results of open globe injuries from traffic accidents.
- To compare outcomes with general open globe injuries.
- To identify preoperative factors affecting visual prognosis after pars plana vitrectomy.
Main Methods:
- Retrospective analysis of patients with open globe injuries undergoing pars plana vitrectomy.
- Data collection included demographics, injury details, and visual acuity.
- Statistical analysis to determine factors influencing visual outcomes.
Main Results:
- 14 traffic accident-related open globe injuries were identified among 355 total cases.
- Ruptures (64.3%) were more common than lacerations (35.7%).
- Initial visual acuity strongly correlated with final visual acuity (P = 0.003).
- Traffic accident injuries had significantly better final visual acuity than the overall group (P = 0.01).
- No cases of endophthalmitis were reported in the traffic accident group.
Conclusions:
- Traffic accident-related open globe injuries generally have better visual prognoses.
- Initial visual acuity is a critical determinant of visual outcome.
- Pars plana vitrectomy is an effective treatment, with low complication rates like endophthalmitis in this cohort.
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