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09:52
Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
Published on: March 8, 2013
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Modern Techniques of Lymphangiography and Interventions: Current Status and Future Development
Maxim Itkin1, Gregory J Nadolski2
1HUP/CHOP Center for Lymphatic Imaging and Interventions, Penn Medicine, Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA, 19104, USA. itkinmax@gmail.com.
Cardiovascular and Interventional Radiology
|December 20, 2017
Summary
Recent advances in lymphatic imaging and interventions, like thoracic duct embolization, are improving fluid balance management. These techniques offer new diagnostic and treatment options for lymphatic pathologies.
Area of Science:
- Vascular Medicine
- Interventional Radiology
Background:
- The lymphatic system's role in fluid balance is critical but historically under-explored due to limited imaging and intervention techniques.
- Recent technological advancements are beginning to illuminate lymphatic system functions and pathologies.
Purpose of the Study:
- To review current and emerging lymphatic imaging and interventional techniques.
- To highlight the expanding therapeutic applications of lymphatic interventions.
Main Methods:
- Intranodal lymphangiography and dynamic contrast-enhanced MR lymphangiography for lymphatic imaging.
- Thoracic duct embolization and interstitial lymphatic embolization for therapeutic interventions.
- Liver lymphatic lymphangiography and embolization for specific conditions.
Main Results:
- New imaging modalities provide unprecedented insight into lymphatic pathology.
- Thoracic duct embolization is now a primary treatment for chylous leaks.
- Lymphatic embolization techniques have expanded to include interstitial and liver applications.
- Successful treatment of postsurgical liver lymphorrhea and protein-losing enteropathy is achievable.
Conclusions:
- Advances in lymphatic interventions offer significant new diagnostic and therapeutic opportunities.
- Future developments in thoracic duct and liver lymphatic procedures hold vast potential for patient care.
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