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Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide
A van der Vlist1, T J Snijders, A M E Stades
1Department of Medical Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.
Abstract:
A 69-year-old man presented with leptomeningeally metastasised pituitary carcinoma, rapidly progressing despite previous treatment with resection, radiotherapy and cabergoline. The patient received temozolomide chemotherapy, resulting in a complete clinical, radiological and biochemical response after 14 cycles, which has been maintained since then. This case lends further support to the role of temozolomide in refractory pituitary tumours.
