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Follicular dendritic cell sarcoma presenting as colonic intussusception.
Masroor Hassan1, Asim Qureshi1, Nadira Mamoon1
1Pathology Department, Shifa International Hospital, Islamabad, Pakistan.
JPMA. the Journal of the Pakistan Medical Association
|December 20, 2017
Summary
Follicular dendritic cell sarcoma (FDCS), a rare cancer, can unusually present as colonic intussusception. This case highlights a novel presentation of this intermediate-grade sarcoma.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Follicular dendritic cell sarcoma (FDCS) is a rare, intermediate-grade malignancy affecting nodal and extranodal sites.
- FDCS presents with two main histological subtypes: conventional and inflammatory pseudotumor-like variant.
Observation:
- This report details an uncommon case of conventional FDCS manifesting as colocolic intussusception.
- The diagnosis was confirmed through characteristic immune-reactivity for dendritic cell markers (CD21, CD23, CD35) and light microscopy.
Findings:
- Conventional FDCS presenting as colonic intussusception is a previously unreported phenomenon.
- The case underscores the diverse morphological spectrum and diagnostic markers of FDCS.
Implications:
- Surgical excision is the primary treatment for FDCS.
- Further research is needed to clarify the roles of adjuvant chemotherapy and radiotherapy in managing FDCS.
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