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Phosphine induced acute cardiotoxicity in children: A need for health awareness

Mehnaz Atiq1, Abdul Sattar Shaikh2

  • 1Aga Khan University Hospital, Karachi, Pakistan.

JPMA. the Journal of the Pakistan Medical Association
|December 20, 2017
PubMed

Insights

Aluminum Phosphate (AP) pesticide poisoning is a serious concern, with high mortality rates. Increased public awareness is crucial to prevent severe outcomes from this effective but toxic agent.

Area of Science:

  • Toxicology
  • Environmental Health

Background:

  • Aluminum Phosphate (AP) is recognized as a cost-effective and potent pesticide.
  • The primary active component, phosphine gas, exhibits high toxicity.

Observation:

  • A case series involving Aluminum Phosphate poisoning was analyzed.
  • Observed mortality rates in the series were significant, reaching 40%.

Findings:

  • The study confirms the high toxicity and lethality of Aluminum Phosphate, with mortality rates comparable to established ranges.
  • A significant percentage of cases resulted in fatalities, highlighting the inherent dangers of AP exposure.

Implications:

  • There is an urgent need to enhance public awareness regarding the risks associated with Aluminum Phosphate.
  • Effective public health strategies and educational campaigns are necessary to mitigate poisoning incidents and improve outcomes.

Keywords:
Phosphine, Aluminum Phosphate, Cardiotoxicity.

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