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Updated: Feb 16, 2026

Unraveling the Role of Discrete Areas of the Rat Brain in the Regulation of Ovulation through Reversible Inactivation by Tetrodotoxin Microinjections
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Orgasm and SCI: what do we know?

Marcalee Alexander1,2,3, Lesley Marson4,5

  • 1Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA. spinalcordmd@live.com.

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Summary
This summary is machine-generated.

Approximately 50% of individuals with spinal cord injuries (SCI) achieve orgasm. Autonomic changes occur during orgasm, and further research into benefits and biases is needed.

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Area of Science:

  • Neuroscience
  • Urology
  • Rehabilitation Medicine

Background:

  • Sexual function is a critical aspect of quality of life.
  • Spinal cord injury (SCI) significantly impacts sexual function, including orgasm and ejaculation.
  • Understanding these impacts is crucial for patient care and rehabilitation.

Purpose of the Study:

  • To determine the prevalence of orgasm and ejaculation in individuals with SCI.
  • To explore associations between orgasm, ejaculation, and subjective/autonomic responses.
  • To investigate potential benefits of orgasm, such as spasticity reduction.

Main Methods:

  • A narrative review of existing literature.
  • Searched databases for terms related to orgasm, ejaculation, and SCI.
  • Included human studies published in English from 1990 to December 2016.

Main Results:

  • About 50% of sexually active individuals with SCI report orgasmic ability.
  • Complete lower motor neuron injuries affecting sacral segments are associated with reduced orgasm achievement.
  • Orgasm in SCI individuals involves elevated blood pressure, similar to able-bodied individuals, necessitating prophylaxis for T6 and above injuries.
  • Dry orgasm occurs in approximately 13% of males.
  • Pharmacological and mechanical interventions may enhance orgasmic potential.

Conclusions:

  • Orgasm achievement post-SCI is possible and varies with injury level and severity.
  • Sympathetically mediated autonomic changes accompany sexual response and orgasm.
  • Future research should explore orgasm's benefits and address study biases.