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Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
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Chem/bio sensing with non-classical light and integrated photonics.

J Haas1, M Schwartz, U Rengstl

  • 1Institute of Analytical and Bioanalytical Chemistry, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany. boris.mizaikoff@uni-ulm.de.

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Quantum photonics enables ultra-sensitive chemical and biological sensors. This review discusses on-chip quantum photonic platforms using N00N states for detecting analytes at ultra-trace levels.

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Area of Science:

  • Quantum optics and photonics
  • Chemical and biological sensing
  • Nanotechnology and materials science

Background:

  • Quantum technology is advancing rapidly in various fields.
  • Harnessing quantum photonics for chem/bio sensing offers ultra-sensitive detection.
  • Progress in fabrication and integration of quantum photonics is key.

Purpose of the Study:

  • To review recent achievements in on-chip chem/bio quantum photonic sensing platforms.
  • To discuss the use of N00N states for enhanced sensitivity.
  • To explore the integration of quantum sensing with recognition chemistries.

Main Methods:

  • Utilizing efficient single-photon sources.
  • Employing waveguiding and sensing structures as optical transducers.
  • Integrating advanced detector materials for enhanced performance.
  • Leveraging N00N states for quantum-enhanced measurements.

Main Results:

  • Demonstrated ultra-trace level detection of (bio)analytes.
  • Achieved sensitivities beyond the standard quantum limit.
  • Showcased the potential of integrated quantum photonic sensors.

Conclusions:

  • On-chip quantum photonic sensors offer a promising route for ultra-sensitive chem/bio detection.
  • The integration of quantum photonics with recognition chemistries is crucial.
  • Future perspectives include fiber-coupled GaAs chips and quantum dots for a robust sensor testbed.