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Senescent chronic kidney disease: The challenges faced and the strategies to overcome

Rajesh Jayaraman1, Elango Ganapathy1, Sudha Balakrishnan1

  • 1Department of Nephrology, Dhanalakshmi Srinivasan Medical College and Hospital, Trichy, Chennai Highway, Perambalur, Tamil Nadu, India.

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|December 22, 2017
PubMed

Insights

Managing chronic kidney disease (CKD) in older adults presents unique challenges, including glomerular filtration rate (GFR) calculation and treatment approach selection. This article aims to provide a consensus for systematic management of elderly CKD patients.

Area of Science:

  • Nephrology
  • Geriatric Medicine
  • Internal Medicine

Background:

  • Chronic kidney disease (CKD) management in elderly patients is complex.
  • Age-related decline in glomerular filtration rate (GFR) increases CKD prevalence in older adults.
  • Challenges include accurate GFR estimation and choosing between disease-oriented and patient-centered care.

Purpose of the Study:

  • To establish a consensus for managing chronic kidney disease in elderly patients.
  • To address practical challenges in elderly CKD care.
  • To propose a systematic approach for managing fragile elderly patients with CKD.

Main Methods:

  • Review of recent advancements in CKD management strategies.
  • Analysis of the evolution of disease-oriented approaches in CKD.
  • Discussion on the implications of age-related GFR decline.

Main Results:

  • CKD is increasingly prevalent in the elderly due to age-related GFR decrease.
  • Significant challenges exist in GFR calculation and treatment strategy selection for older adults.
  • A refined disease-oriented approach has emerged over the last decade.

Conclusions:

  • A systematic approach is needed for managing elderly CKD patients.
  • Consensus on practical issues can improve care for this population.
  • Addressing age-specific challenges is crucial for effective CKD management in the elderly.

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