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Hyperplastic Polyps and Gastroduodenal Pseudomelanosis
Akanksha Agrawal1, Deepanshu Jain2, Vivian Arguello3
1Department of Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA, USA.
Case Reports in Gastrointestinal Medicine
|December 23, 2017
Summary
This study reports a rare case of upper gastrointestinal pseudomelanosis in a patient with gastric hyperplastic polyps. The findings suggest a potential association between pseudomelanosis and polyps, warranting further investigation.
Area of Science:
- Gastroenterology
- Pathology
- Endoscopy
Background:
- Pseudomelanosis is a rare upper gastrointestinal finding.
- It is characterized by hemosiderin deposits in the lamina propria.
- The etiology and prognosis remain poorly understood.
Observation:
- A 72-year-old female on oral iron supplementation presented with upper GI symptoms.
- Endoscopy revealed gastric hyperplastic polyps with pseudomelanosis.
- Pseudomelanosis was observed in both the stomach and duodenum.
Findings:
- This is the first reported case of concomitant gastric and duodenal pseudomelanosis with gastric hyperplastic polyps.
- The presence of pseudomelanosis without gastritis raises questions about its association with hyperplastic polyps.
- Oral iron supplementation may play a role in the development of pseudomelanosis.
Implications:
- Further prospective studies and case reporting are needed to understand the natural history of pseudomelanosis.
- The association between pseudomelanosis and hyperplastic polyps requires further investigation.
- Clinicians should consider pseudomelanosis in patients with upper GI polyps and iron supplementation.
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