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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

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Migraine in Women.

Susan W Broner¹, Sarah Bobker¹, Louise Klebanoff¹

¹Department of Neurology, Weill Cornell Medical College, New York, New York.

Seminars in Neurology

|December 23, 2017

Summary

Migraine disproportionately affects women, with hormonal influences playing a key role throughout their lives. This review details hormonal impacts on migraine, aiding practitioners in managing this neurological disorder.

Area of Science:

Neurology
Endocrinology
Women's Health

Background:

Migraine is a prevalent neurological disorder with a 3:1 female-to-male ratio, particularly after puberty.
Estrogen's hormonal influence is significant, though migraine pathophysiology remains incompletely understood.
Hormonal fluctuations across the female lifespan impact migraine frequency and severity.

Purpose of the Study:

To review the current understanding of migraine in women, focusing on hormonal influences.
To explore migraine epidemiology, pathophysiology, and treatment strategies.
To examine migraine during key reproductive and hormonal transition periods.

Main Methods:

Comprehensive literature review of recent studies on migraine and hormonal factors.

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Analysis of epidemiological data and pathophysiological mechanisms.

Evaluation of treatment strategies and risks associated with exogenous hormone use.

Main Results:

Migraine prevalence increases in women post-puberty, linked to estrogen fluctuations.
Specific considerations for migraine during pregnancy, postpartum, breastfeeding, perimenopause, and menopause are discussed.
Risks and benefits of exogenous hormone therapy and stroke risk in women with migraine aura are reviewed.

Conclusions:

Understanding the hormonal basis of migraine in women is crucial for effective management.
Tailored treatment strategies are needed for different life stages and hormonal states.
Further research is warranted to optimize care for women experiencing migraine.