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Updated: Aug 12, 2026

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
[Internal irradiation doses in patients during the diagnostic use of colloidal radiopharmaceutics]
Abstract:
The assessment of the human organs and body systems exposed to radiation was based on the investigation of colloidal radiopharmaceuticals employed in the USSR for liver and spleen visualization. Seven radiopharmaceuticals (functional analogs: 3 were imported to the USSR, 4--made in this country) were investigated. Pharmacokinetics of the agents was studied by a human counter that permitted obtaining quantitative data on their distribution and elimination from the body. A computerized program based on the heterogeneous model of a "standard" man. Dose calculation results have shown that the critical organ for all investigated radiopharmaceuticals is the liver, the radiation dose in it being at 90-120 microSv/MBq and the mean effective equivalent dose at 14 +/- 1 microSv/MBq.
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