[ASBMR topics from clinical to translational research.]

Aging and senescence are main topics in this ASBMR Annual Meeting as both the Aurbach lecture and Avioli award lecture focused on the topic. Osteoporosis is one of typical age-related disease and elimination of senescent cells is new strategy of treatment for osteoporosis. Antibody and synthetic antagonist or agonist which modify the action of hormone and growth factor, an inhibitor of ectopic bone formation and a stimulator of muscle mass have been developed as a new drug for metabolic bone diseases and skeletal dysplasias.