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Yolk-Shell Nanostructures: Design, Synthesis, and Biomedical Applications.
Li-Sen Lin1,2, Jibin Song1,2, Huang-Hao Yang1
1MOE key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Advanced Materials (Deerfield Beach, Fla.)
|December 28, 2017
Summary
Yolk-shell nanostructures (YSNs) offer unique properties for diverse applications. This review details their synthesis strategies and significant biomedical uses, including drug delivery and cancer therapy.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- Yolk-shell nanostructures (YSNs) feature a core within a hollow cavity and a porous outer shell.
- YSNs exhibit unique structural characteristics, physicochemical properties, and broad application potential.
Purpose of the Study:
- To provide a comprehensive overview of YSN design, synthesis, and biomedical applications.
- To highlight the advantages of YSNs in various biomedical fields.
Main Methods:
- Categorization of synthesis strategies into hard-templating, soft-templating, self-templating, and multimethod combination.
- Discussion of template-based and template-free synthesis approaches.
- Exploration of combined methods for complex YSN fabrication.
Main Results:
- Detailed examination of YSN applications in biosensing, bioimaging, drug/gene delivery, and cancer therapy.
- Emphasis on the superior performance of YSNs in these biomedical contexts.
- Identification of future research directions for YSN development.
Conclusions:
- YSNs represent a promising class of nanomaterials with significant potential in biomedicine.
- Advancements in synthesis and application continue to drive YSN research.
- Further exploration is needed to fully realize the therapeutic and diagnostic capabilities of YSNs.
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