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Nursing Ethical Principles I01:22

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Qualitative Analysis03:46

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For solutions containing mixtures of different cations, the identity of each cation can be determined by qualitative analysis. This technique involves a series of selective precipitations with different chemical reagents, each reaction producing a characteristic precipitate for a specific group of cations. Metal ions within a group are further separated by varying the pH, heating the mixture to redissolve a precipitate, or adding other reagents to form complex ions.
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The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System
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Ethical challenges experienced by clinical research nurses:: A qualitative study.

Mary E Larkin1, Brian Beardslee2, Enrico Cagliero1

  • 1Massachusetts General Hospital, USA; Harvard Medical School, USA.

Nursing Ethics
|December 29, 2017
PubMed
Summary

Clinical research nurses face unique ethical challenges, balancing patient advocacy with protocol implementation. These conflicts arise from dual obligations and impact the nurse-participant relationship.

Keywords:
Advocacyclinical researchclinical research nursedilemmasethicsnursingresearch

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Area of Science:

  • Nursing Research
  • Bioethics
  • Clinical Trials

Background:

  • Clinical investigation is an expanding nursing specialty.
  • The clinical research nurse role presents unique objectives, settings, and nurse-participant dynamics.
  • Potential ethical conflicts exist between protocol adherence and patient advocacy.

Purpose of the Study:

  • To describe the ethical challenges encountered by clinical research nurses.
  • To understand the nature of these challenges within their practice context.

Main Methods:

  • Qualitative descriptive study design.
  • Individual interviews conducted with participating nurses.
  • 12 nurses self-identified experiencing ethical challenges.

Main Results:

  • Key themes included inability to ensure probable good/do no harm and navigating dual obligations (nurse vs. research nurse).
  • Subthemes revealed conflicted allegiances regarding protocol implementation, participant needs, scientific advancement, and therapeutic vs. research relationships.
  • Ethical issues are central to the nurse-participant relationship, patient advocacy, and protocol execution.

Conclusions:

  • Ethical challenges specific to the clinical research nurse role were identified.
  • Further research is needed to understand the scope and frequency of these challenges.
  • Support systems for resolving these ethical dilemmas require further investigation.