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Amiodarone-associated bilateral vestibulopathy
Robert Gürkov1, Leonardo Manzari2, Alexander Blödow3
1Department of Otorhinolaryngology, LMU Munich, Munich, Germany. robert.guerkov@med.uni-muenchen.de.
Summary
Amiodarone may cause bilateral vestibulopathy (BVP), a balance disorder. This study found a 12% prevalence of BVP in patients with a history of Amiodarone treatment, suggesting a link.
Area of Science:
- Neurology
- Ophthalmology
- Otolaryngology
Background:
- Bilateral vestibulopathy (BVP) is a disabling condition resulting from impaired vestibular organs.
- Common causes include ototoxic drugs, infections, and autoimmune diseases, but many cases are idiopathic.
Purpose of the Study:
- To investigate the potential link between Amiodarone use and idiopathic bilateral vestibulopathy.
- To determine the prevalence of prior Amiodarone treatment in patients diagnosed with idiopathic BVP.
Main Methods:
- Retrospective analysis of medical records from five dizziness clinics.
- Identification of patients diagnosed with idiopathic BVP.
Main Results:
- 126 patients with idiopathic BVP were identified.
- A 12% prevalence of BVP was observed in patients with a history of Amiodarone treatment (15 out of 126).
Conclusions:
- The findings support the hypothesis that Amiodarone can induce bilateral vestibulopathy.
- Recommends vestibular examination for patients on Amiodarone experiencing balance issues to enable early intervention.
