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Updated: Feb 16, 2026

Assembly and Characterization of Polyelectrolyte Complex Micelles
Published on: March 2, 2020
Antioxidant-spotting in micelles and emulsions
Carolina Aliaga1, Amaia López de Arbina1, Camila Pastenes2
1Facultad de Química y Biología, Universidad de Santiago de Chile, Casilla 40 Correo 33, Santiago de Chile, Chile; Centro para el Desarrollo de la Nanociencia y la Nanotecnología, CEDENNA, Chile.
Abstract:
A simple protocol is described for locating the site of action of an antioxidant (AO) in a micro-heterogeneous mixture, based on the pattern of the reactivity curve towards the AO of a series of 4-alkanoyl TEMPO radicals. The resulting cut-off curves yield information regarding the hydrophobic microenvironment surrounding the reactive AO group, and its accessibility by the probe. Convex curves are an indication of an AO located in a more hydrophilic environment, while concave plots originate from AOs in a more hydrophobic location in the micro-heterogeneous system.
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