Evaluation of anterior segment parameters in patients with Turner syndrome using Scheimpflug imaging

To compare the anterior segment parameters in patients with Turner syndrome (TS) as measured by the Pentacam HR-Scheimpflug imaging system with those of healthy control subjects.

This cross-sectional prospective study included 35 patients with TS and 30 age-matched controls. Corneal topographic analysis was performed using the Pentacam HR-Scheimpflug imaging system (Oculus, Wetzlar, Germany). The power of the corneal astigmatism, mean keratometry (Km) values for the both front and back surfaces of the cornea, maximum keratometry (Kmax), central corneal thickness (CCT), corneal volume (CoV), white-to-white diameter (WTW), chamber volume (CaV), angle and anterior chamber depth (ACD) values were recorded.

The mean age of TS subjects was 17.2 ± 6.1 years; of controls, 16.4 ± 5.7 years. All participants were female. There was a significant difference in the mean values of WTW (11.3 ± 0.5 mm vs 12.0 ± 0.4 mm [P < 0.001]), CaV (148.4 ± 33.5 mm³ vs 191.9 ± 27.6 mm³ [P < 0.001]), and ACD (2.8 ± 0.3 mm vs 3.1 ± 0.2 mm [P < 0.001]) between TS versus group and the control group. The mean values of the power of the corneal astigmatism, Km values for the both front and back of the corneal surface, Kmax, CCT, CoV, and angle values were similar between groups (P > 0.05 for each one).

There was a reduction in CaV, ACD, and WTW measurements in TS patients compared with controls.