Related Experiment Video
Updated: Feb 16, 2026

The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System
Published on: April 25, 2012
Respiratory and Laryngeal Function in Teachers: Pre- and Postvocal Loading Challenge
Nicole E Herndon1, Anusha Sundarrajan1, M Preeti Sivasankar1
1Department of Speech, Language, and Hearing Research, Purdue University, West Lafayette, Indiana.
Teachers experienced increased vocal tiredness and effort after a 1-hour vocal loading challenge. However, key physiological measures like lung volume and voice quality remained within normal ranges, suggesting resilience.
Area of Science:
- Occupational health
- Speech and hearing science
- Vocal pedagogy
Background:
- Teachers are at high risk for voice disorders due to demanding vocal tasks.
- Understanding the physiological impact of vocal loading is crucial for teacher well-being.
Purpose of the Study:
- To investigate laryngeal and respiratory physiological changes in teachers following a standardized vocal loading challenge.
- To quantify changes in vocal effort, tiredness, and acoustic/aerodynamic parameters.
Main Methods:
- Twelve teachers participated in a 1-hour vocal loading task (reading aloud in noise).
- Vocal effort, tiredness, sound pressure level, lung volumes, cepstral peak prominence, and low/high spectral ratio were measured before and after the challenge.
Main Results:
- Significant increases in vocal effort, vocal tiredness, utterance length, and sound pressure level were observed post-challenge.
- A significant decrease in lung volume (% vital capacity per syllable) indicated altered breathing patterns.
Conclusions:
- A 1-hour vocal loading challenge increases subjective vocal effort and tiredness in teachers.
- Objective laryngeal and respiratory measures showed resilience, with parameters like lung volume and voice quality remaining largely within normal limits.
- Further research is necessary to elucidate the long-term effects of vocal use and loading on teachers' voices.
Related Concept Videos
Physiology of Respiration I: Functions of the Respiratory System
Fundamental Processes in Respiration:
pre-mRNA Processing
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl...
Pre-mRNA Processing: Modification of pre-mRNA Ends
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a cap to the 5' end of the growing transcript. In this process, a 5' phosphate is replaced by modified guanosine that has a methyl group attached (7-methyl guanosine). This 5' cap helps...
Anatomy of Respiratory System II: Lower Respiratory Tract
The Larynx
It is located between the pharynx and the trachea, acts as a passageway for air, and hosts several critical structures, such as the epiglottis, vocal cords, and glottis. The epiglottis acts as a gateway, guiding food to the...
The Respiratory System
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....

