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[Sensitivity pattern of Staphylococcus aureus isolated from quarter milk from cattle]
U Vecht1, H J Wisselink, H M Vette
1Centraal Diergeneeskundig Instituut, Lelystad.
Tijdschrift Voor Diergeneeskunde
|March 1, 1989
Summary
Bovine Staphylococcus aureus strains show significant resistance to penicillin, oxytetracycline, and streptomycin. Testing for beta-lactamase production is recommended alongside antibiotic susceptibility to guide mastitis treatment.
Area of Science:
- Veterinary Microbiology
- Antimicrobial Resistance
Context:
- Bovine mastitis is a significant concern in dairy farming.
- Staphylococcus aureus is a primary causative agent of mastitis.
- Antimicrobial susceptibility testing is crucial for effective treatment.
Purpose:
- To assess the antimicrobial susceptibility of Staphylococcus aureus strains isolated from bovine milk.
- To evaluate the correlation between agar dilution and diffusion methods for susceptibility testing.
- To determine the prevalence of beta-lactamase production in these strains.
Summary:
- 319 Staphylococcus aureus strains from bovine milk were tested for antimicrobial susceptibility using MIC and agar diffusion methods.
- High resistance rates were observed for penicillin (38.4%), oxytetracycline (21.2%), and streptomycin (11.5%).
- Strong correlations were found between dilution and diffusion methods for oxytetracycline and streptomycin, but weaker for penicillin.
Impact:
- Recommends routine beta-lactamase testing alongside antibiotic susceptibility for staphylococci.
- Suggests registration of sulfone compounds like dapsone for veterinary use due to high efficacy.
- Advises against using new broad-spectrum antibiotics for mastitis due to unchanged resistance patterns.