Open splenectomy for Varicella zoster induced spontaneous splenic rupture
Mark Christopher Sykes1, Bilal Azhar2, Laurence John3
1Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom.
Introduction:
Here we present a case of atraumatic splenic rupture secondary to varicella infection requiring emergency splenectomy. The presentation was as would be expected for epstein barr virus (EBV) related splenic injury, which is well documented in the literature. Dermatological findings however suggested varicella zoster, and viral serology subsequently confirmed the diagnosis.
Presentation Of Case:
A young Romanian male presented to the emergency department with peritonism without preceding trauma. Free fluid on USS was aspirated as frank blood and cross-sectional imaging demonstrated a ruptured spleen. He underwent emergency splenectomy and recovered well. During his presentation he was noted to have an erythematous rash with different rates of evolution raising the suspicion for Varicella Zoster. This was subsequently confirmed on viral serology.
Discussion:
A number of precedents have been identified for spontaneous splenic rupture, however Varicella Zoster has only been reported a handful of times. A number of surgical options are available for splenic rupture, and guidelines exist for traumatic splenic injury. There is limited guidance on the most effective surgical management for spontaneous splenic ruptures with haemodyamic compromise.
Conclusion:
Atraumatic splenic rupture should be considered as an important differential in those presenting with abdominal pain and peritonism without a history of preceding trauma. Haematological and infectious diagnoses should be sought to identify causation for the splenic rupture.
Related Concept Videos
Spontaneous and Induced Mutations
Spontaneity
Induced-fit Model
Enzymes exhibit substrate specificity, meaning that they can only bind to certain substrates. This is mainly determined by the shape and chemical...
Induced Pluripotent Stem Cells
Induced Pluripotent Stem Cells
Somatic...
Induced Electric Dipoles
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...


