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Related Concept Videos

Bipolar Disorder01:30

Bipolar Disorder

1.0K
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
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Classification of Illness01:17

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The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
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Factors Affecting Illness01:18

Factors Affecting Illness

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When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
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Concepts of Health and Illness01:29

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Health is a condition of the body, mind, and spirit where an individual remains free from illness. Similarly, wellness is an active state, including living a lifestyle that promotes physical, mental, and emotional health. Physical health is critical for the overall well-being and can be affected by lifestyle, activity level, diet, and behavior. The highest attainable standard of health is a fundamental and universal human right. Consider Lisa, a fifteen-year-old born with congenital...
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Dimensions of Health and Illness01:21

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The factors influencing the health-illness continuum can be internal or external and may or may not be under conscious control. They are related to the following eight human dimensions, and each dimension is interrelated to one other.
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Bipolar Junction Transistors (BJTs) are essential elements in electronic circuits, playing a crucial role in the functionality of amplifiers, memories, and microprocessors. These transistors can be designed as NPN or PNP based on their doping patterns. They consist of three layers: the emitter, base, and collector. The configuration of these layers and their respective doping levels—with N-type or P-type impurities—define the transistor's type and its operational...
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Related Experiment Video

Updated: Feb 16, 2026

Developing a Rat Model for Bipolar Disorder
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[BIPOLAR DISORDER AS A MULTI-SYSTEM ILLNESS].

Daphna Fenchel1, Yechiel Levkovitz1,2, Moshe Kotler1,2

  • 1Beer Yaakov-Ness Ziona Mental Health Center, Beer Yaakov, Israel.

Harefuah
|January 3, 2018
PubMed
Summary
This summary is machine-generated.

Bipolar disorder significantly impacts physical health, increasing risks for cardio-metabolic conditions and mortality. Integrated treatment addressing both mental and physical symptoms is crucial for improving patient outcomes.

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Area of Science:

  • Psychiatry and Internal Medicine
  • Understanding Bipolar Disorder as a Multi-System Illness

Background:

  • Bipolar disorder is a chronic condition associated with high patient distress and a 30% suicide rate.
  • Over 70% of bipolar patients exhibit cardio-metabolic symptoms, a higher prevalence than in other psychiatric disorders.
  • Cardiovascular disease is a primary cause of increased mortality in bipolar disorder patients, with a 1.5-2 fold higher risk.

Purpose of the Study:

  • To highlight the multi-system nature of bipolar disorder.
  • To emphasize the link between psychiatric and physical comorbidities.
  • To advocate for integrated treatment approaches.

Main Methods:

  • Review of existing literature on bipolar disorder comorbidities.
  • Analysis of epidemiological data on physical health in bipolar patients.
  • Synthesis of current perspectives on bipolar disorder management.

Main Results:

  • Bipolar disorder patients exhibit high rates of medical and psychiatric comorbidities.
  • Cardio-metabolic conditions and cardiovascular disease significantly increase mortality risk.
  • Medical comorbidities are linked to poorer prognosis in bipolar disorder.

Conclusions:

  • Bipolar disorder should be viewed as a multi-system illness affecting overall physical health.
  • Optimal treatment requires addressing both psychiatric and physical symptoms.
  • Integrated care strategies are essential for improving prognosis in bipolar disorder.