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Updated: Feb 16, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
For Debate: Constitutional and Non-Constitutional Delay of Growth and Puberty
1University of Munich, Dr von Haunersches Kinderspital, Germany,
Abstract:
Herewith a definition of constitutional delay of growth and puberty shall be given. Whereas constitutional delay of growth and puberty is a hereditary variant of normal growth and development occurring in both sexes and is irrelevant to the familial height, non-constitutional delay is secondary to a variety of underlying disorders like chronic diseases, malnutrition, persistence of psychologic problems or hormonal anomalies. Constitutional delay occurs in boys and girls and will end in normal final height within the familial height range.
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