Related Experiment Video
Updated: Feb 16, 2026

Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging
Published on: June 16, 2023
Dutch Resolution of a configurationally stable [5]helquat
Lukáš Severa1, Petra Sázelová1, Ivana Císařová2
1The Institute of Organic Chemistry and Biochemistry of the Czech, Academy of Sciences, Prague 6, Czech Republic.
Abstract:
Synthesis and nontrivial optical resolution of a helicene-like dication, helquat 1, has been accomplished. Starting with gram scale of the racemic helquat 1 sample, Dutch Resolution using family of 3 tartrate anions was key to achieve successful separation of M and P helical enantiomers of 1. Hundreds of milligrams of each enantiomer of this configurationally stable C2 -symmetric helquat have been obtained. Racemization barrier of 1 has been determined. To our knowledge this is the first report on Dutch Resolution performed with a helicene-like compound. Moreover, there are no literature precedents for Dutch Resolution of chiral quaternary ammonium cations.
Related Concept Videos
Electron Configuration of Multielectron Atoms
Controller Configurations
Control-system compensation involves various configurations, most commonly series or cascade compensation, in which the controller...
Electron Configurations
The relative energies of the subshells determine the order in which atomic orbitals are filled (1s, 2s, 2p, 3s, 3p,...
Configurations of BJT
The common base configuration is noted for its high voltage gain, positioning it as an ideal choice for single-stage amplifier circuits, such as microphone pre-amplifiers. A notable...
Stability of Equilibrium Configuration
A stable equilibrium occurs when a system tends to return to its original position when given a small displacement, and the potential energy is at its minimum. An example of a stable equilibrium is when a cantilever beam is fixed at one end and a weight is attached to the other end. If the weight...
5-Number Summary
In a box plot, the minimum and maximum data values represent the lower and upper whiskers in the graph, and the median is designated as the center of the box in the chart. The first quartile and third...

