Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Evidence for Evolution02:55

The Evidence for Evolution

48.5K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
48.5K
Real Number System01:27

Real Number System

1.2K
The real number system includes all numbers used for counting, measuring, and comparing quantities. Natural numbers are the basic counting numbers: 1, 2, 3, and so on. Integers expand this set by including zero and negative whole numbers: ..., –3, –2, –1, 0, 1, 2, .... Rational numbers are those that can be expressed as the ratio of two integers m/n, where n≠0. This includes fractions like 1/2​, integers such as 46, and decimals that terminate, such as 0.17, or...
1.2K
Real Number Operations01:27

Real Number Operations

349
The concept of real numbers includes all the values that can be represented on a continuous number line. The system began with basic counting values used for enumeration. It later expanded to include values that represent the absence of quantity and opposites of the counting values. When situations required expressing parts of a whole or dividing quantities evenly, values capable of representing such proportions were developed. When written using decimal notation, these values can end or repeat...
349
Real Gases: Effects of Intermolecular Forces and Molecular Volume Deriving Van der Waals Equation04:01

Real Gases: Effects of Intermolecular Forces and Molecular Volume Deriving Van der Waals Equation

39.3K
Thus far, the ideal gas law, PV = nRT, has been applied to a variety of different types of problems, ranging from reaction stoichiometry and empirical and molecular formula problems to determining the density and molar mass of a gas. However, the behavior of a gas is often non-ideal, meaning that the observed relationships between its pressure, volume, and temperature are not accurately described by the gas laws.
39.3K
Real Zeros of Polynomials01:27

Real Zeros of Polynomials

195
Polynomials are algebraic expressions of terms with variables raised to non-negative integer powers. A central aspect of analyzing polynomial functions is determining their real zeros—values of the variable for which the polynomial evaluates to zero. These values represent the x-intercepts of the polynomial’s graph.The Rational Zeros Theorem lists possible rational solutions for a polynomial equation with integer coefficients. If f(x)=anxn+....+a0​, then every rational zero is...
195
Trigonometric Functions of Real Numbers01:30

Trigonometric Functions of Real Numbers

449
The unit circle—a circle with a radius of one, centered at the origin of the coordinate plane—serves as the foundational framework for defining trigonometric functions. In this context, arc length refers to the distance measured along the circumference of the circle between two points, and it provides a way to represent real numbers geometrically. Each real number t corresponds to an arc length measured counterclockwise from the positive x-axis around the circle. The coordinates of...
449

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recenti progressi in medicina·2026
Same author

Comments on: Italian Medicines Agency's reform and time until pricing and reimbursement decisions: a time-to-event analysis.

Global & regional health technology assessment·2026
Same author

Safety of influenza vaccine during the vaccination campaign 2021/2022 in Italy: a self-controlled case series study.

Vaccine·2026
Same author

[The regional network for CAR-T therapies in the Lazio Region: a governance model for innovation and sustainability.]

Recenti progressi in medicina·2026
Same author

[Use of paracetamol during pregnancy: scientific evidence, media alerts, and implications for public health].

Epidemiologia e prevenzione·2026
Same author

[Talking about data, what is real?]

Epidemiologia e prevenzione·2025
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
Same journal

Recenti progressi in medicina·2026
See all related articles

Related Experiment Video

Updated: Feb 16, 2026

A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

12.1K

[Real-world evidence.]

Luca De Fiore1, Antonio Addis2

  • 1Associazione Alessandro Liberati network italiano Cochrane.

Recenti Progressi in Medicina
|January 4, 2018
PubMed
Summary
This summary is machine-generated.

Real-world evidence (RWE) from sources like electronic health records aids pharmaceutical development. However, randomized controlled trials remain the gold standard for minimizing bias in clinical research.

More Related Videos

Real-Time Void Spot Assay
06:39

Real-Time Void Spot Assay

Published on: February 10, 2023

2.7K
Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

1.6K

Related Experiment Videos

Last Updated: Feb 16, 2026

A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

12.1K
Real-Time Void Spot Assay
06:39

Real-Time Void Spot Assay

Published on: February 10, 2023

2.7K
Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

1.6K

Area of Science:

  • Medical Informatics
  • Clinical Research Methodology
  • Pharmaceutical Sciences

Background:

  • Real-world evidence (RWE) is increasingly discussed at medical conferences, encompassing data from electronic health records, registries, and observational studies.
  • RWE is utilized to support accelerated approval pathways for new pharmaceutical products and medical devices.
  • While valuable, RWE complements, but does not replace, traditional clinical research methods.

Discussion:

  • Randomized controlled trials (RCTs) are the established gold standard for clinical research due to their ability to minimize bias and rigorously evaluate intervention effectiveness.
  • Pragmatic trials and quasi-randomized trials offer potential for reduced study length and cost.
  • The primary challenge for RWE is data quality, not the context of evidence gathering.

Key Insights:

  • RWE is a significant topic in medical and pharmaceutical discussions.
  • Data quality is the critical factor determining the utility of real-world evidence.
  • Balancing RWE with RCTs is essential for robust clinical validation.

Outlook:

  • Future research may focus on improving RWE data quality and integration methods.
  • The role of RWE in regulatory decision-making is likely to expand.
  • Hybrid approaches combining RWE with traditional trial designs may emerge.