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[Pembrolizumab for the treatment of melanoma: updates and perspectives.]

Vanna Chiarion Sileni1, Mario Mandalà2, Paola Queirolo3

  • 1Istituto Oncologico Veneto, Padova.

Recenti Progressi in Medicina
|January 4, 2018
PubMed

Checkpoint inhibitors immunotherapy was a breakthrough in anti-tumor treatments. Anti-PD-1 monoclonal antibodies are now a standard of treatment for advanced melanoma patients, with a 3-year overall survival of over 50% and a low rate (<20%) of severe toxicities in the phase 3 studies. The aim of this review was to report the most important updates on anti-PD-1 drug pembrolizumab from ASCO (American Society of Clinical Oncology) and ESMO (European Society for Medical Oncology) 2017 Annual Meetings.

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