[Treatment of acute myocardial infarction in 2017]

Giovanni Cimmino1, Davide D'Andrea2, Ciro Mauro2

  • 1Dipartimento di Scienze Cardiotoraciche e Respiratorie, Università degli Studi della Campania "Luigi Vanvitelli", Napoli.

Giornale Italiano Di Cardiologia (2006)
|January 4, 2018
PubMed

Insights

Acute myocardial infarction (AMI) is a critical cardiac emergency. Updated guidelines reflect advances in antithrombotic strategies, revascularization, and cardiac rehabilitation for improved patient outcomes.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Acute myocardial infarction (AMI) is a life-threatening condition stemming from acute coronary syndromes, characterized by plaque rupture and thrombus formation.
  • The condition presents clinically as ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) based on ECG findings.

Purpose of the Study:

  • To summarize recent advancements in the management of ST-segment elevation myocardial infarction (STEMI).
  • To present the updated European guidelines for STEMI management, incorporating new therapeutic and interventional strategies.

Main Methods:

  • Review of recent pharmacological and interventional management strategies for AMI.
  • Analysis of advancements in antithrombotic therapies, percutaneous coronary intervention (PCI) access sites, stent technology, lipid management, and cardiac rehabilitation.
  • Synthesis of evidence to inform guideline revisions by the European Task Force on ST-Elevation Myocardial Infarction.

Main Results:

  • Significant improvements in pharmacological and interventional treatments for AMI over the past three decades.
  • Emerging evidence supporting new antithrombotic strategies, radial artery access for PCI, timely revascularization, and next-generation stents.
  • Enhanced focus on comprehensive care including lipid management and structured cardiac rehabilitation programs.

Conclusions:

  • The updated European guidelines incorporate significant progress in STEMI care.
  • These revisions aim to optimize patient outcomes through evidence-based strategies in antithrombosis, revascularization, and post-discharge care.
  • Continuous evaluation and integration of new therapeutic advances are crucial for managing AMI effectively.

Related Concept Videos

Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
4.5K
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.3K
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
762
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
1.1K
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
1.2K
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
521