Reference ranges for rotational thromboelastometry in male Sprague Dawley rats
Related Experiment Video
Updated: Feb 16, 2026

Isolation and Culture of Primary Retinal Müller Cells from Sprague-Dawley (SD) Rats
Published on: June 17, 2025
Mariana Vigiola Cruz1,2,3, Jenna N Luker1, Bonnie C Carney1
1Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC USA.
Background:
A functional coagulation assay was used to investigate the extrinsic pathway of coagulation on citrated whole blood samples from healthy adult male Sprague Dawley rats using the mini cup and pin system.
Methods:
Reference values for coagulation parameters from forty-three animals were calculated using data obtained from the ROTEM® delta hemostasis analyzer with the EXTEM test.
Results:
The following ranges, presented as the 2.5-97.5 percentiles, were established: CT [18-77], CFT [20-80], α [73-86], MCF [53-70], and ML [1-22], along with others.
Conclusions:
These reference ranges can be used in future studies in rats to identify clinically significant coagulopathies.
Related Concept Videos
Variation: Normal Distribution, Range, and Standard Deviation
Range
15.9; 16.1; 15.2; 14.8; 15.8; 15.9; 16.0; 15.5
Measurements of the amount of soda in a 16-ounce can vary since different subjects record these measurements or since the exact amount - 16 ounces of liquid, was not...
Inertial Frames of Reference
Non-inertial Frames of Reference
Infertility in Males
¹H NMR: Long-Range Coupling
In alkenes, spin information is communicated via σ–π overlap, as seen in allylic (four-bond) and homoallylic (five-bond) couplings. These coupling interactions are stronger when the σ bond is parallel to the alkene...

