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Is there a relationship between spondyloarthritis and periodontitis? A case-control study
Wilson Bautista-Molano1,2,3, Desirée van der Heijde1, Robert Landewé4,5
1Rheumatology Department, Leiden University Medical Center, Leiden, The Netherlands.
RMD Open
|January 5, 2018
Summary
Patients with spondyloarthritis (SpA) showed a lower frequency and severity of periodontitis compared to healthy individuals. This study found no positive association between SpA and periodontitis in Colombian patients.
Area of Science:
- Periodontology
- Rheumatology
- Immunology
Background:
- Spondyloarthritis (SpA) is a group of inflammatory diseases.
- Periodontitis is a chronic inflammatory condition affecting the gums.
- The relationship between SpA and periodontitis requires further investigation.
Purpose of the Study:
- To compare the prevalence and severity of periodontitis in SpA patients versus healthy controls.
- To evaluate clinical, serological, and microbiological periodontal parameters.
- To determine any association between SpA and periodontitis.
Main Methods:
- Included 78 SpA patients (naive to bDMARDs) and 156 matched healthy controls.
- Periodontal assessment by calibrated periodontologists using CDC-AAP criteria.
- Measured IgG1/IgG2 antibodies against Porphyromonas gingivalis and identified periodontopathic bacteria.
Main Results:
- Periodontitis diagnosed in 56% of SpA patients vs. 69% of controls (P≤0.01).
- Severe periodontitis observed in 3% of SpA patients vs. 12% of controls (P≤0.01).
- No significant differences in periodontal variables, antibodies, or bacteria between groups; no positive association found (OR: 0.57).
Conclusions:
- SpA patients exhibited a lower, not higher, frequency and severity of periodontitis.
- Findings suggest no positive association between SpA and periodontitis in this Colombian cohort.
- Further research may explore potential protective factors in SpA patients.
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